LivDetox

Liver Detoxification

LivDetox

DESCRIPTION
LivDetox� tablets, provided by Nutrition Dynamics, Inc., contain several nutrient and herbal ingredients shown to maintain

liver structure and function in response to environmental toxins

FUNCTIONS
LivDetox� contains several dietary constituents that have been shown to support against various toxic environmental stresses that affect the function and structure of the liver.

Choline, betaine, and methionine are involved in methyl group metabolism, which is essential for normal liver function. Choline, as an integral component of lecithin (phosphatidylcholine), is used for synthesis and maintenance of normal cell membranes. Choline deficiency results in steep increases in serum enzyme markers of liver injury. Animals deficient in choline and inositol have an excess liver accumulation of fat. Inositol and choline supplementation of animals prone to fatty livers prevents this liver dysfunction.

Taraxacum (dandelion) has been traditionally used as a detoxifying herb working principally on the liver and gallbladder. This herb stimulates elimination of toxins that may result from infection or pollution and is one of the strongest cholagogues and choleretics known.

Silybum marianum, milk thistle, is rich in n flavonoids known collectively as silymarin. Silymarin has also been shown to support healthy liver function under a variety of environmental stress factors such as alcohol consumption and exposure to pollutants and other potentially harmful substances. Silymarin compounds are known for their antioxidant activities preventing damaging lipid peroxidation by excessive free radical levels.

Cynara scolymus (artichoke) has been used medicinally for centuries. Similar to milk thistle it is beneficial to the liver as it protects it against environmental and infection-generated toxins. Extracts of artichoke can stimulate the flow of bile from the liver and prevent cholestasis. It also can protect liver cells from oxidative damage. Cynara�s effectiveness in treating hepato-biliary dysfunction is thought to be due to its content of caffeoylquinic acids, e.g. cynarin, and flavonoids.

Curcumin has been demonstrated to be a potent chemopreventive compound against chemical-induced hepatocarcinogenesis, as well as liver injury from toxins such as carbon tetrachloride.

INDICATIONS
LivDetox� may be a useful dietary supplement for individuals who wish to maintain the structure and function of a healthy liver.

Three Tablets Contain:
Choline Bitartrate 1,500mg
L-Methionine     15mg
Inositol    150mg
Betaine HCl                 75mg
Lecithin (Soya) Granulars      75mg
Niacin                               10mg
Taraxacum     50mg
Curcumin    50mg
Silybum marianum                          50mg
Cynara    50mg

SUGGESTED USE
Adults take 3 tablets daily or as directed by physician.

REFERENCES

Anonymous. Taraxacum officinale. Altern Med Rev 1999;4:112-4.

Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories. Med Klin 1999;94 Suppl 3:84-9.

Christian JS, Rege RV. Methionine, but not taurine, protects against formation of canine pigment gallstones. J Surg Res 1996;61:275-81.

Chuang SE, Kuo ML, Hsu CH, et al. Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis. Carcinogenesis 2000;21:331-5.

Favari L, Perez-Alvarez V. Comparative effects of colchicine and silymarin on CCl4-chronic liver damage in rats. Arch Med Res 1997;28:11-7.

Flora K, Hahn M, Rosen H, et al. Milk thistle (Silybum marianum) for the therapy of liver disease [see comments]. Am J Gastroenterol 1998;93:139-43.

Kenney JL, Carlberg KA. The effect of choline and myo-inositol on liver and carcass fat levels in aerobically trained rats. Int J Sports Med 1995;16:114-6.

Kropacova K, Misurova E, Hakova H. Protective and therapeutic effect of silymarin on the development of latent liver damage. Radiats Biol Radioecol 1998;38:411-5.

Lieber CS. Pathogenesis and treatment of liver fibrosis in alcoholics: 1996 update. Dig Dis 1997;15:42-66.

Park EJ, Jeon CH, Ko G, et al. Protective effect of curcumin in rat liver injury induced by carbon tetrachloride. J Pharm Pharmacol 2000;52:437-40.

These statements have not been evaluated by the Food and Drug Administration. .

This product is not intended to diagnose, treat, cure, or prevent any disease.